The visit to Astana is being made upon an official invitation by his Kazakh counterpart Yerlan Idrisov.
During his stay in Astana, Zarif will hold separate talks with his Kazakh counterpart and Kazakh President Nursultan Nazarbayev.
The two foreign ministers are scheduled to discuss the latest regional and international developments.
President Hassan Rouhani paid an official visit to Kazakhstan last September to take part in Iran-Kazakhstan economic forum. Rouhani delivered a speech in Astana University.
Meanwhile, the Kazakh president is scheduled to visit Tehran by the end of this spring.