One of Turkey's big trade union groups is staging a two-day strike to support continuing anti-government protests in a number of cities.
The left-wing Kesk trade union confederation, representing some 240,000 workers, accused the government of committing "state terror".
Protests and clashes with police continued into the night on Monday.
A second death in the protests has been confirmed by the governor's office in the southern city of Antakya.
Abdullah Comert, 22, a member of the youth wing of the opposition Republican People's Party, was "seriously wounded... after gunfire from an unidentified person," the governor's office said, adding that he died later in hospital.
Earlier, the Turkish Doctors' Union said 20-year-old Mehmet Ayvalitas was hit by a car on Sunday which ignored warnings to stop and ploughed into a crowd of protesters in the Mayis district of Istanbul.
Prime Minister Recep Tayyip Erdogan went ahead with a trip to Morocco and insisted the situation was improving.
The strike on Tuesday and Wednesday is expected to affect schools and universities along with government offices.
In a statement, Kesk said: "The state terror implemented against entirely peaceful protests is continuing in a way that threatens civilians' life safety."
The confederation, representing 11 unions, accused the government of undermining democracy.
Mr Erdogan remained defiant on Monday in the face of continuing violence, dismissing any suggestion of a "Turkish Spring".
In a televised news conference he said: "The main opposition party CHP has provoked my innocent citizens. Those who make news [and] call these events the Turkish Spring do not know Turkey."
After arriving in Morocco, he insisted the situation was "calming down".
"On my return from this visit, the problems will be solved," he told reporters.
In contrast, President Abdullah Gul, adopted a more conciliatory tone, defending the right to protest while urging calm.
"If there are different opinions, different situations, different points of view and dissent, there is nothing more natural that being able to voice those differences," he was quoted as saying by the Anatolia news agency.
There were further clashes on Monday between police and protesters which continued into a fourth night in Istanbul and the capital, Ankara.
Thousands of demonstrators again gathered in Istanbul's Taksim Square, the focus of the protests.
Many protesters shouted "Tayyip, resign!" while waving red flags and banners and blowing whistles, and tear gas could be seen wafting over the square.
Police also used tear gas again to disperse protesters near Mr Erdogan's office in the Besiktas district of the city.
Hundreds of protesters were reported to have gathered in the early hours of Tuesday in Ankara where they were met by more tear gas and water cannon.
Share values in Turkey were hit badly by the unrest, with the main share index falling by 10.47%.
The cost of insuring Turkish debt rose to a two-month high.
In a sign of continuing concern in Washington, US Secretary of State John Kerry spoke of "excessive use of force" by the police.
"We obviously hope that there will be a full investigation of those incidents and full restraint from the police force," he said.
The protests began on 28 May over plans to redevelop Gezi Park near Taksim Square in Istanbul.
They soon mushroomed, engulfing several cities and including political demands.
Unrest was also reported on Sunday in the western coastal city of Izmir, Adana in the south and Gaziantep in the south-east.
Protesters accuse the Turkish government of becoming increasingly authoritarian.
They fear Mr Erdogan's Justice and Development Party (AKP) is trying to impose conservative Islamic values on the officially secular country and infringe on their personal freedoms, correspondents say.
Officials said more than 1,700 people have been arrested in demonstrations in 67 towns and cities, though many have since been released.